Description
Athletes use aromatase inhibitors like Letrozole to prevent various estrogenic side effects such as gynecomastia, water retention and bloating. In addition, Letrozole lowers estrogen levels and stimulates the body’s natural production of testosterone. Thus, steroid users mainly use Letrozole during steroid treatment and post-cure therapy medication.
Unlike SERMs, aromatase inhibitors (AIs) don’t just block estrogen’s effects at the receptor—they stop it from being created in the first place.
AIs work by inhibiting the enzyme aromatase, which is responsible for converting testosterone into estradiol (E2). That means AIs reduce total serum estrogen levels throughout the body—not just in breast tissue, but everywhere estrogen exerts influence.
